The New York Mets defeated the Cardinals 4-2 in a game at Busch Stadium, with Clay Holmes' performance continuing his strong start to the season. Holmes allowed two earned runs on four hits and five strikeouts and three walks, ending his night with a 6-3 victory. The victory was the third consecutive start for the Mets, marking a 3-1 win over the Pirates. The rotation will change on Wednesday with Freddy Peralta's return from his underwhelming Opening Day start. The Mets will also see Kodai Senga make his first start of the season, with the Japanese right-hander set to begin showing potential as a trusted rotation piece.