Brewers starter Jacob Misiorowski and four Milwaukee relievers set a new MLB record with 20 strikeouts on Opening Day against the White Sox, leading to a 14-2 victory over the team. This was an especially notable achievement for Misiorow, who allowed a leadoff homer to the White Series's Chase Meidroth, the first Opening Day leadoff in Chicago's history. The team also set a franchise record and tied the MLB record for the most team strikeouts in a nine-inning game. The first time a team has recorded that many in nine innings on Opening day was the first time they did so.