A study by the University of California, San Diego, has found that it may be possible to predict the risk of dementia two decades in advance using a simple blood test. The study involved a cohort of 2,766 women aged 65 to 79 in the U.S. who did not have cognitive impairment at the start of the study. Participants were recruited between 1996 and 1999 and assessed for up to 25 years. Researchers found that 1,311 women developed either MCI or dementia at the conclusion of the research. There were also significant associations between p-tau217 and dementia and MCI for women older than 70, and women with the APOE-related gene. Despite some limitations, researchers noted that only older women were examined and that dementia was not examined by subtype.