Clinical Trial Finds NAC May Help Cats with CKD
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By Lisa Selvaggio
Published on March 13, 2026.
A recent study has found that N-Acetylcysteine (NAC) may help cats with chronic kidney disease (CKD), which is progressive and difficult to manage. The study involved 50 cats who were previously diagnosed with IRIS stage 2 to 4 CKD and showed decreased renal mass bilaterally, changes in renal cortical echogenicity, and rough surface contours of the kidneys. The researchers incorporated NAC into the typical intravenous fluid therapy used during acute exacerbations of the disease. They compared the results to those of cats who received NAC in a saline solution intravenously, while the placebo group only received a saline intravenously. The team found that incorporating NAC may potentially help cats experiencing acute on chronic kidneys disease.
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