A man had a rare reaction to getting a new tattoo, with his skin completely necrotic, killing it. The red cross tattoo on his neck disappeared three months after it was placed there. The patient developed lumps on both sides of his neck, which grew gradually, and these types of growths are known as "necrotic" ulcers. Despite being prescribed antibiotics and topical corticosteroids, his symptoms continued to worsen. Doctors examined the patient and found a large necrotal ulcer on the base of his skin, which had spread to the deeper layers of his body. They also found dead cells, immune cells, and scar tissue. The diagnosis was confirmed as granulomatous lymphadenitis, a condition where immune cells form a wall around persistent infections or foreign materials. Following surgery and short-term hormone therapy, the man made a full recovery. This case is only the second known case of necrosis following a tattoo.