Brett McGurk, a CNN global affairs analyst, has highlighted the ten key issues that matter most, including the destruction of Iran's air defenses, and uncertainty within Iran's leadership. The US and Israel appear to have air dominance over Iran, allowing U.S. and Israeli aircraft to fly freely as long as this conflict continues. The top priority for US and Israeli military commanders is to degrade Iran’s missile capabilities, particularly its launchers. Despite efforts by Iran to replace its Supreme Leader, Ali Khamenei, there is no clear successor to him. The UK, France, and Germany may also join in military strikes against Iran, suggesting a potential coalition could form.