Researchers at Iowa State University have collected the memorial records of 505 people who died with Chronic Fatigue Syndrome (CFS/ME), a disease that can fundamentally impact a person's life. The study found that four major themes included systemic neglect and institutional failure, clinical neglect and failure, social disconnection, and personal burden. The deceased individuals did not necessarily die from CFS/MI, but the disease seemed to have a significant impact on their quality of life. Patients also recounted their experiences and the impact the disease had on their loved ones' death. The researchers suggest that research on CFS orME is inadequate due to the true burden of the disease and suggested that the US National Institutes of Health would need to increase research funding by 40-fold.