Crude oil prices are expected to rise when trading begins due to fears that a war between the U.S. and Iran will lead to a major supply disruption. The massive airstrikes against Iran have killed several top leaders, including Supreme Leader Ayatollah Ali Khamenei. The international benchmark, Brent crude oil, could see even bigger gains. The outcome of the conflict depends on whether it leads to a prolonged disruption to traffic through the Strait of Hormuz, a crucial chokepoint for global oil trade. President Donald Trump has agreed to talk with Iran, leaving open the possibility of a potential deescalation.