Stanford Cures Type-1 Diabetes in Mice Without Insulin or Immune Suppression
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By Andy Corbley
Published on March 2, 2026.
Stanford University has successfully cured type-1 diabetes through a double-transplant method, using mice without needing insulin or immune suppression. The method involved transplanting pancreatic islet cells and blood stem cells from a healthy mouse, creating a hybrid immune system that simultaneously stabilizes the recipient's immune system. This was achieved without any side-effects. The researchers believe this approach could be transformative for those with type 1 diabetes or other autoimmune diseases, as well as those who need solid organ transplants. For six months, the treated mice needed no insulin injection or medication to suppress graft-versus-host disease, an immune-system response that can be debilitating. The research holds much promise for future treatments of type-2 diabetes, rheumatoid arthritis, and lupus.
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