Weed is actually ‘rarely justified’ to treat anxiety or depression, says major scientific review
By Mckenzie Beard
Published on March 20, 2026.
A major scientific review by the University of Sydney has found that medical marijuana is rarely justified to treat anxiety, depression or PTSD. The study, billed as the "largest review of medical cannabis to date," found little evidence that it could effectively treat these conditions. The researchers also found no benefit for treating bipolar disorder, anxiety, ADHD, OCD, anorexia nervosa or psychotic disorders. For people with cocaine-use disorder, medical cannabis increased cravings, which they believe could make their dependency worse. However, the researchers identified promising results for cannabis use disorder, which can reduce cannabis smoking when administered alongside psychological therapy. Despite these findings, Dr. Jack Wilson, lead author of the study, said the findings raise serious questions about whether medicinal cannabis should be approved for conditions like depression, anxiety and PTSD.
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