U.S. stocks closed higher on Wednesday, with the Dow Jones Industrial Average up 0.66% and the S&P 500 gaining 0.5% to 6,591.90. Meanwhile, Urban-gro's stock surged by 416.95%, reaching an intraday high of $36.29 and setting a new 52-week high. The company's merger with IPG aims to centralize sponsorship revenue and expand into new markets like Bangladesh and the UAE. Sarepta Therapeutics saw its stock jump by 34.98%, following promising early results from its siRNA programs, bolstering confidence in their potential treatments for muscular dystrophies. Additionally, Advanced Micro Devices (NASDAQ:AMD) saw a rise of 7.26%, following reports of upcoming CPU price hikes due to tightening supply and increasing demand from AI-centric data centers.