Stephen Colbert started his episode of The Late Show with a parody of Pope Leo XIV, where he used a diss track titled "They Not Pious" to criticize President Donald Trump for being a "bestie" with Jeffrey Epstein and calling him "senile." The song was inspired by Kendrick Lamar's "Not Like Us" diss track against Drake. The lyrics included a reference to the pope's criticism of religious rhetoric being used to advocate for war or promote war. In response, Vice President JD Vance and others within the MAGA movement have criticized the pope for engaging in political discussions. The pope has responded by reiterating his stance against those who manipulate religion for political gain.