US Vice President JD Vance has departed for Pakistan to engage in talks on ending the US-Israeli war with Iran, with expectations of positive results. Speaking to reporters, Vance said that President Donald Trump had given clear guidelines for the talks, which will be productive if Iran does not 'play' US. The move to have Vance lead the US delegation seen as a sign of Iran's wariness with US Special Envoy Steve Witkoff and Trump's son-in-law Jared Kushner, who had previously led indirect negotiations about Iran's nuclear programme. The format of the negotiations was not immediately disclosed. Key issues, including control over the Strait of Hormuz, the future of Iran’s nuclear programme, and whether Israel’�s invasion of Lebanon is subject to the ceasefire, have not been resolved yet.