Amy Schumer, a 44-year-old actress, has been candid about her weight loss journey after being diagnosed with Cushing syndrome, a hormonal condition that causes elevated levels of cortisol and can cause death if left untreated. She lost 50 pounds in less than a decade, largely due to a combination of factors such as plastic surgery and Mounjaro. Schumer also experimented with weight loss medication Ozempic, which some celebrities have used to slim down, but found it difficult to bear due to its side effects and made it difficult for her to be a present parent for her son, 6, and to look after her child.