At least three US service members have been killed and five more seriously wounded in the US and Israel's joint attack on Iran, according to US Central Command. At least nine people were killed in a direct Iranian missile strike near Jerusalem, marking the deadliest incident in Israel since Iran began retaliating to a wave of joint US-Israel strikes. Several people have died and dozens injured following protests at the US consulate compound in Karachi. Iranian Deputy Foreign Minister Saeed Khatibzadeh said President Trump crossed a "very dangerous red line" following US-Israeli attacks.