Amazon's One Medical is launching a national GLP-1 program, combining prescription and ongoing primary care. The move comes as demand for weight-loss drugs increases, but also raises concerns about gaps in care and clinical oversight. The program is integrated with Amazon Pharmacy, allowing patients to see upfront pricing and get medications delivered. The company is positioning its approach as more integrated than many existing options, embedding GLP1 treatment within primary care and focusing on nutrition, lifestyle changes, and managing side effects. The GLOP-1 market is evolving rapidly, with new drug formats, more approved uses and broader insurance coverage expected to expand access.