CM Punk and Roman Reigns are set to compete in a match at WWE WrestleMania 42. The rivalry between these two men has been high-profile throughout their career, with Punk's focus on ending the undefeated streak of undefeated opponent Undertaker's undefeated streak at the event. Other notable moments include his feud with The Rock, where he and The New Nexus targeted The Master of the 619 and his heel faction The Straight Edge Society. Despite his brief stint with All Elite Wrestling, Punk had many memorable run-ins with stars such as MJF, Eddie Kingston, and Samoa Joe. His feud with Orton was successful, elevating both men to upper-midcard status and making Punk over as the ultimate underdog. His rivalry with Reigns began in late 2008, but ended in early 2011 when he rekindled their rivalry in early 2021. Despite this, Punk's career was largely overshadowed by ongoing feud with John Cena and The Rock.