Dr. Joseph D'Orazio and his wife, Linda, experienced the unexpected diagnosis of Angelman syndrome, a rare disease that changes their lives. The diagnosis changed their lives, with frequent sleep disturbance and medical appointments. The family adjusted their lives and learned to cope with chronic exhaustion and stress. Despite being an emergency physician, D'Orrazio was unprepared for the emotional transition and loss of control over the future he had imagined for his child. He shared his personal experiences with CNBC Cures and their professional lives.